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Adult-to-adult living related liver transplantation : initial experience

Journal Volume 64 - 2001
Issue Fasc.1 - Original articles
Author(s) P. Lerut, O.Ciccarelli, F. M. Roggen, R. Reding, P. F. Laterre, B. Lengele, M. Janssen, Ch. Chardot, S. Clement de Clety, E. Danse, P. Goffette, R. Matteme, E. Sokal, Y Horsmans, J. B. Otte
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Liver Transplant Program, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 1200 Brussels, Belgium. Department of Digestive Surgery (ProL R. Detry) ; (1) Pediatric Surgery (Prof. J. B. Otte) ; (2) Intensive Care (Prof. M. S. Reynaert) ; (3) Radiology (Prof. B. Maidague) ; (4) Pediatrics (Prof. J. P. Buts) (5) Hepatogastroenterology (Prof. A. Geubel).

The number of adult patients on the liver transplantation waiting lists is growing steadily. Adult living related liver transplantation (LRLT) represents the ultimate means to expand the donor pool. The success of this model of "small for size" grafting relies on strict donor and recipient selection. The choice of the graft (2 left and 4 right hepatectomies) was made on the minimal ratio between estimated graft and recipient body weights (0.8-1%), necessary to meet the recipient's metabolic demands. Our experience with six adults is reported. Donor morbidity was minimal (one wound infection) ; there was no mortality. Four (66%) recipients are doing well, two died of infectious complications. All recipients had a complicated post-transplant course. Due to its complexity, both in donor and recipient, LRILT should only be developed very carefully in experienced liver transplant centers.

© Acta Gastro-Enterologica Belgica.