Liver transplantation for neurologic manifestations of Wilson's disease
| Journal | Volume 68 - 2005 |
| Issue | Fasc.4 - Symposium |
| Author(s) | J.-Ch. Duclos-Vallée, Ph. Ichai, F. Woimant, D. Samuel |
| Full article |
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| Centre Hépato-Biliaire - Hôpital Paul-Brousse, Assistance Publique-Hôpitaux de Paris, Villejuif, France, Service de Neurologie - Hôpital Lariboisière, Assistance Publique-Hôpitaux de 75018 Paris, France. |
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Wilson's disease, a copper-overload disease, is an inherited as an autosomal recessive trait. The majority of clinical presentation include hepatic and neurologic manifestations. Hepatic manifestations are represented by end-stage liver cirrhosis or fulminant hepatitis with acute failure. Neurological form is represented by severe motor abnormalities such as ataxia, involuntary move- ments, hypertonia and loss of speech. Sometime these neurological features lead to bedridden states. |
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© Acta Gastro-Enterologica Belgica. |
